Table 4. Association of different clinicopathological factors with growth patterns.
| Items | Destructive N (%) | Papillary N (%) | Alveolar N (%) | P-value |
|---|---|---|---|---|
| Number of cases | 196 (70.3) | 38 (13.4) | 45 (16.1) | |
| Gender | 0.069 | |||
| Female | 21 (10.7) | 9 (23.7) | 8 (17.8) | |
| Male | 175 (89.3) | 29 (76.3) | 37 (82.2) | |
| Agea (years) | 65 (40–87) | 65 (42–77) | 66 (39–80) | 0.324 |
| Histiotype | <0.0001 | |||
| Adenocarcinoma | 43 (21.9) | 38 (100) | 12 (26.7) | |
| Squamous cell | 110 (56.1) | — | 18 (40.0) | |
| Large cell | 29 (14.8) | — | 13 (28.9) | |
| others | 14 (7.1) | — | 2 (4.4) | |
| Localisation | 0.264 | |||
| Left lung | 89 (45.4) | 12 (31.6) | 21 (46.7) | |
| Right lung | 107 (54.6) | 26 (68.4) | 24 (53.3) | |
| Stage | 0.245 | |||
| IA | 47 (24.0) | 16 (42.1) | 14 (31.1) | |
| IB | 60 (30.6) | 13 (34.2) | 17 (37.8) | |
| IIA | 8 (4.1) | 2 (5.3) | 2 (4.4) | |
| IIB | 51 (26.0) | 3 (7.9) | 6 (13.3) | |
| IIIA | 14 (7.1) | 1 (2.6) | 2 (4.4) | |
| IIIB | 16 (8.2) | 3 (7.9) | 4 (8.9) | |
| T-status | 0.194 | |||
| T1 | 55 (28.1) | 18 (47.4) | 16 (35.6) | |
| T2 | 107 (54.6) | 16 (42.1) | 24 (53.3) | |
| T3 | 18 (9.2) | 1 (2.6) | 1 (2.2) | |
| T4 | 16 (8.2) | 3 (7.9) | 4 (8.9) | |
| N-status | 0.282 | |||
| N0 | 132 (67.3) | 32 (84.2) | 34 (75.6) | |
| N1 | 50 (25.5) | 5 (13.2) | 9 (20.0) | |
| N2 | 14 (7.1) | 1 (2.6) | 2 (4.4) | |
| Type of operation | 0.081 | |||
| (Bi)lobectomy | 129 (65.8) | 32 (84.2) | 31 (68.9) | |
| Pneumonectomy | 67 (34.2) | 6 (15.8) | 14 (31.1) | |
| Size of the tumora (cm) | 4.00 (1–16) | 2.95 (1–13) | 3.10 (1–14) | 0.049 |
| Radiotherapy | 0.385 | |||
| No | 157 (80.1) | 34 (89.5) | 36 (80.0) | |
| Received | 39 (19.9) | 4 (10.5) | 9 (20.0) |
a
For continuous variables, figures are median (range).