Figure 2.
Quantitive PCR analysis of DNA adducts on genomic DNA from control and CDDP-treated (6 mg i.p. kg−1) pxn65 and pxn100 xenograft tumours. (A) Denaturing polyacryalmide gel analysis of the NRAS PCR product amplified from genomic DNA taken from duplicate pxn100 xenograft tumours. (B) Quantification of PCR products from analysis of CDDP-treated pxn65 and pxn100 tumours. Open square symbols, dotted line=pxn65 and closed circle symbols, solid line=pxn100 (n=2).
