Table 1. Reasons for noneligibility or nonevaluability for response.

Reasona	Arm A	Arm B	Arm C	Arm D
Presence or history of CNS metastasis		1	1	1
No measurable lesion	1
Patient not metastatic		1
Early discontinuation		3	1	8
Early death		1
Response not properly assessed	1
>1 line palliative chemotherapy		1
Total bilirubin >1.5 UNL				1
ASAT and ALAT >5 UNL				1

^aA patient may have more than one reason.