Skip to main content
. 2004 Sep 21;91(8):1580–1590. doi: 10.1038/sj.bjc.6602175

Table 3. Predicted BRCA1/2 carrier probabilities for a breast cancer case whose mother developed breast cancer.

  Age at onset of breast cancer for mother (years)
Index age at onset (years) 30 40 50 60 70
30
 BRCA1 0.400 (0.566) 0.223 (0.415) 0.075 (0.244) 0.045 (0.103) 0.042 (0.049)
 BRCA2 0.318 (0.036) 0.221 (0.034) 0.196 (0.037) 0.153 (0.030) 0.102 (0.020)
           
40
 BRCA1 0.212 (0.407) 0.087 (0.270) 0.025 (0.144) 0.014 (0.056) 0.013 (0.025)
 BRCA2 0.211 (0.033) 0.107 (0.028) 0.082 (0.027) 0.062 (0.021) 0.041 (0.013)
           
50
 BRCA1 0.056 (0.228) 0.020 (0.137) 0.006 (0.067) 0.003 (0.024) 0.003 (0.011)
 BRCA2 0.180 (0.035) 0.080 (0.027) 0.061 (0.024) 0.047 (0.018) 0.032 (0.011)
           
60
 BRCA1 0.023 (0.079) 0.008 (0.043) 0.002 (0.020) 0.001 (0.007) 0.001 (0.003)
 BRCA2 0.134 (0.028) 0.058 (0.020) 0.045 (0.017) 0.036 (0.012) 0.025 (0.007)
           
70
 BRCA1 0.019 (0.022) 0.006 (0.011) 0.002 (0.005) 0.001 (0.001) 0.001 (0.000)
 BRCA2 0.080 (0.016) 0.034 (0.011) 0.028 (0.009) 0.024 (0.006) 0.017 (0.004)

Corresponding probabilities using BRCAPRO within parentheses.