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. 2004 Oct 12;91(9):1694–1702. doi: 10.1038/sj.bjc.6602183

Table 5. Relationship between ERα, ERβ and other histopathological variables.

Factor ERα IHC ERα RT–PCR ERβIHC ERβ RT–PCR
Stage low P=0.019 low P=0.014 n.s. n.s.
  (MW) n=160 (MW) n=127 (CS, MW) n=138 (CS, MW) n=127
Grade low P<0.0005 low P<0.0005 n.s. n.s.
  (MW) n=160 (MW) n=127 (CS, MW) n=138 (CS, MW) n=127
Size n.s. n.s. larger P=0.076* larger P=0.025
  (CS, MW) n=158 (CS, MW) n=125 (MW) n=136 (MW) n=125
Nodal status negative P=0.048 negative P=0.057 n.s. n.s.
  (CS) n=131 (CS) n=108 (CS) n=110 (CS) n=108
Lymphovascular Invasion n.s. n.s. present P=0.067* present P=0.043
  (CS, MW) n=159 (CS) n=126 (CS) n=137 (CS) n=126
PgR positive P<0.0005 positive P<0.0005 n.s. positive P=0.056
  (MW) n=146 (CS) n=110 (CS, MW) n=138 (CS) n=110
Ki67 low P<0.0005 low P<0.0005 high P=0.034 n.s.
  (MW) n=141 (CS) n=108 (MW) n=133 (CS, MW) n=108

Statistical test used was chi-square (CS), Mann-Whitney (MW); n.s.=not significant.

*

using a cut-off of 60% positive cells for ERβ1.