Table 3. Summary of changes in plasma/serum markers of angiogenesis.
|
Baseline |
||||
|---|---|---|---|---|
| Marker | Controls (n=39) | Patients (n=23) | Week 4 | Week 8 |
| Serum VEGF (pg ml−1) | 20 (1199.3) | 185 (218.552)* | 170 (60.600) | 180 (213.326) |
| Plasma VEGF (pg ml−1) | 70 (221.024) | 280 (555.927)* | 200 (486.197)** | 120 (177.708)** |
| Serum VCAM-1 (ng ml−1) | 460 (133.83) | 640 (165.6)* | 620 (182.6) | 645 (256.3) |
| Serum E-selectin (ng ml−1) | 42 (18.37) | 43.5 (19.6) | 43 (19.2) | 44 (25.2) |
| Serum vWF (IU dl−1) | 103 (21.82) | 138 (26.9)* | 138 (29.6) | 146 (27.9) |
| Plasma PAI-1 (μg l−1) | 7.1 (5.1) | 16.5 (10.5)* | 15 (12.7) | 14 (11.7) |
Median values (standard deviation).
*
Significantly increased (P<0.05).
**
Significant decrease (P<0.05).