Fig. 3.

Calcium wave propagation is altered by superfusate flow. A, Superfusate flow turned off. Propagation is symmetric. B, Superfusate flow from leftto right. Propagation is highly asymmetric. Propagation in the direction of superfusate flow is greatly extended, whereas propagation in the direction opposite the flow is reduced. The two images were obtained from nearby regions of the same retina. Waves were evoked by mechanical stimulation. The tip of the stimulating probe is near the center of the images. Shown are recordings from a whole-mount retina. Scale bar, 50 μm.