Table 3. Cumulative incidence of haematologic malignancy in Fanconi anaemia patients obtained using the Kaplan–Meier (KM) approach by not adjusting for competing risk events, and estimated by adjusting for competing risk events (CR).
| Overall (%) | A (%) | C (%) | G (%) | O (%) | ||
|---|---|---|---|---|---|---|
| N (HEM) | 755 (120) | 207 (30) | 78 (19) | 46 (10) | 414 (60) | |
| % Censored | KM | 84 | 86 | 76 | 78 | 86 |
| CR | 58 | 67 | 44 | 57 | 55 | |
| 10 year | KM | 6.3 | 5 | 15 | 11 | 5 |
| CR | 5.9 | 4 | 11 | 7 | 5 | |
| 20 year | KM | 22.6 | 20 | 42 | 32 | 19 |
| CR | 17.8 | 15 | 27 | 21 | 14 | |
| 30 year | KM | 39.0 | 45 | 53 | 45 | 34 |
| CR | 27.8 | 31 | 32 | 31 | 23 | |
| 40 year | KM | 47.8 | 52 | 68 | 45 | 44 |
| CR | 31.8 | 34 | 35 | 31 | 27 |
Column 3 (‘Overall’) shows the cumulative incidence for all the 755 patients. Columns 4, 5, 6 and 7 show the cumulative incidence estimates for patients in complementation groups A, C, G and O (mostly nontyped patients and a small number of patients in uncommon complementation groups). The sample size is denoted N. The number of haematologic malignancy events is denoted by HEM and is given in parentheses in the second row.