Table 2. ORs and 95% CIs of ovarian cancer and borderline tumour according to BRCA1 mutations and CA125.

	Ovarian cancer			Borderline tumour
	Case/Ctrl	OR	95% CI	Case/Ctrl	OR	95% CI
BRCA1a
Negative	459/1419	1.0	Referent	190/568	1.0	Referent
Positive	19/2	29	6.6–120	0/0	—	—
CA125
Negative	407/1342	1.0	Referent	155/523	1.0	Referent
Positive (overall)	71/79	3.1	2.2–4.4	35/45	2.5	1.6–4.1
Lag time (years)b
0–1	56/167	13	4.2–37	23/69	32	4.0–260
2–3	68/201	2.1	0.8–5.5	31/92	1.9	0.7–5.6
4–5	75/224	1.5	0.6–4.2	30/90	6.0	1.5–24
6–7	77/231	2.3	0.9–5.5	27/81	1.7	0.6–4.7
8–9	72/216	1.7	0.6–4.4	20/60	0.4	0.0–3.4
10–14	99/292	3.3	1.5–7.2	47/140	1.6	0.5–4.9
15+	31/90	13	1.4–130	12/36	1.5	0.1–17

OR=odds ratio; CI=confidence interval.

^a816delGT, 1135insA, 1675delA and/or 3347delAG.

^bFor controls, time between serum sampling and diagnosis for the belonging case.