Table 2.
Metformin (n=16)
|
Berberine (n=15)
|
|||
---|---|---|---|---|
Baseline | End point | Baseline | End point | |
HbA1c (%) | 9.15 ± 0.57 | 7.72 ± 0.43** | 9.47 ± 0.65 | 7.48 ± 0.40** |
FBG (mmol/L) | 9.96 ± 0.64 | 7.16 ± 0.71** | 10.63 ± 0.88 | 6.85 ± 0.53** |
PBG (mmol/L) | 20.53 ± 1.87 | 12.86 ± 0.77** | 19.83 ± 1.66 | 11.05 ± 0.92** |
Fasting insulin (μU/ml) | 27.3 ± 4.4 | 22.9 ± 5.2 | 29.1 ± 5.3 | 24.0 ± 5.5 |
Postprandial insulin (μU/ml) | 125.3 ± 29.8 | 110.5 ± 21.4 | 120.4 ± 31.4 | 116.0 ± 26.9 |
Triglyceride (mmol/L) | 1.19 ± 0.12 | 1.17 ± 0.13 | 1.13 ± 0.13 | 0.89 ± 0.03* |
Total cholesterol (mmol/L) | 4.31 ± 0.28 | 4.27 ± 0.15 | 4.40 ± 0.21 | 3.83 ± 0.09* |
HDL-C (mmol/L) | 1.25 ± 0.06 | 1.31 ± 0.08 | 1.33 ± 0.10 | 1.22 ± 0.04 |
LDL-C (mmol/L) | 2.55 ± 0.38 | 2.43 ± 0.11 | 2.47 ± 0.13 | 2.36 ± 0.06 |
Data are means ± SEM. Compared with baseline:
P<0.05,
P<0.01