Table 2. Age-adjusted and multivariate-adjusted cancer mortality rate ratios according to increments of total daily physical activity among all men, never smokers, and current or former smokers.

	MRR (95% CI) per 4 MET-h per daya,b
Cancer mortality	Age-adjustedc	Multivariate-adjustedc,d	Multiple imputationc,e
Total physical activity
No. of subjects	n=28 880	n=28 880	n=40 708
All men	0.86 (0.80–0.92)	0.88 (0.82–0.94)	0.89 (0.84–0.95)
By smoking status
Never	0.84 (0.74–0.95)	0.83 (0.72–0.95)	0.88 (0.79–0.97)
Current and former	0.87 (0.81–0.95)	0.90 (0.83–0.97)	0.89 (0.83–0.97)

^aCI=confidence interval; MRR=mortality rate ratios.

^bMET=metabolic equivalent, 4 MET correspond to physical activities of moderate effort for 1 h day⁻¹.

^cMRRs were adjusted for age (continuous), body mass index (continuous), smoking status and pack-years of smoking (never, former <20 pack-years, former 20–39 pack-years, former ⩾40 pack-years, current <20 pack-years, current 20–39 pack-years, current ⩾40 pack-years), alcohol consumption (current drinker, former drinker, never drunk), educational level (less than high school, high school graduate, and more than high school), history of diabetes (yes, no), and parental history of cancer (yes, no, not known).

^dComplete case analysis discarded missing values on any covariate.

^eMultiple imputation analysis based on five imputed data sets of the analytic cohort and estimates combined using Rubin's method.