Table 3. Incidence of interstitial pneumonitis cases among 8090 breast cancer patients registered in DBCGa and treated with radiation therapy by age and cancer stage, Denmark 1994–2004.
| Number of breast cancer patients (%) | Number of IP patients (%) | Incidence rate per 100 000 person-years (95% CI) | |
|---|---|---|---|
| IP radiation-induced | |||
| Overall | 8090 (100%) | 14 (100%) | 31.5 (18.1–51.5) |
| Age groups (years) | |||
| <50 | 2971 (36.7%) | 2 (14.3%) | 11.7 (2.3–37.4) |
| 50–70 | 4577 (56.6%) | 10 (71.4%) | 40.5 (20.8–71.8) |
| >70 | 542 (6.7%) | 2 (14.3%) | 7.3 (1.6–26.0) |
| Cancer stagea | |||
| Localised cancer, no metastasis | 3444 (42.6%) | 1 (7.1%) | 4.7 (0.4–22.0) |
| Regional metastases | 4311 (53.2%) | 13 (92.9%) | 61.1 (34.2–101.5) |
| Distant metastases | 93 (1.1%) | 0 (−) | — |
| Unknown | 242 (3.0%) | 0 (−) | — |
a
Danish Breast Cancer Corporation Group database.