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. 2008 May 27;98(11):1784–1789. doi: 10.1038/sj.bjc.6604389

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Copyright © 2008 Cancer Research UK

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Pixel-by-pixel ΔR2^* map of murine brain with Mel57-VEGF-A₁₆₅ metastases (A). Reference gradient-echo image post-USPIO is shown in (B). The ΔR2^* map is displayed with a high cutoff threshold in the tumour areas (region inside the box) and a low cutoff threshold outside tumour regions, to better visualise the differences in regional blood volume between brain regions that do not include tumour. An example of two ROIs chosen for ΔR2^* and ΔR2 quantitation (see Table 1) in healthy brain regions – in the striatum (indicated by the horizontal arrow) and in the cortex (indicated by the vertical arrow) – is shown in the reference gradient-echo image.