Table 2. Expression of genes in NR and SR samples.
| Basal expression | Expression 2 h after 2 Gy x-irradiation | |||||
|---|---|---|---|---|---|---|
|
Mean (95% conf. interval)
|
Mean (95% conf. interval)
|
|||||
| NR | SR | P-value* | NR | SR | P-value* | |
| CCNB1 | 2.859 (2.233–3.484) | 3.001 (2.341–3.659) | 0.7487 | 2.341 (2.153–2.529) | 2.267 (2.093–3.441) | 0.552 |
| CDKN1A | 0.748 (0.141–1.356) | 0.722 (0.573–0.872) | 0.9298 | 11.241 (8.607–13.874) | 6.795 (5.5541–8.05) | 0.0021** |
| GADD45A | 0.052 (0.014–0.09) | 0.088 (0.024–0.151) | 0.3256 | 17.168 (8.961–25.374) | 17.062 (9.436–24.688) | 0.9832 |
| BBC3 | 0.045 (0.02–0.069) | 0.065 (0.042–0.087) | 0.1991 | 23.045 (11.434–34.817) | 10.585 (7.916–13.255) | 0.552 |
Mean values represent the expression level of each gene normalised to the house keeping control HPRT and for irradiated samples, relative to unirradiated controls.
*ANOVA test for heterogeneity between NR and SR groups, P-values **P<0.0021, significant.