Table 3. Genotype and allelic frequencies of two polymorphisms assessed in 25 breast cancer patients treated with radiotherapy, 11 normal reactors (NR) and 14 severe reactors (SR).

	Radiosensitivity groups n (%)		Odd ratio
Genotype and allele	Severe reactors n=14	Normal reactors n=11	(95% conf. interval)	Significance level P
CDKN1A (codon 31 C>A Ser/Arg)
Genotypes
C/C	10 (71)	8 (73)
C/A	4 (29)	2 (18)	N/A	1.00*
A/A	0 (0)	1 (9)	N/A	0.47*
Allelic frequencies
C	24 (86)	18 (82)
A	4 (14)	4 (18)	N/A	0.72*
TP53 (codon 72 G>C Arg/Pro)
Genotypes
G/G	9 (64)	6 (55)
G/C	3 (21)	3 (27)	N/A	1.00*
C/C	2 (14)	2 (18)	N/A	1.00*
Allelic frequencies
G	21 (75)	15 (68)
C	7 (25)	7 (32)	0.71 (0.17–2.92)	0.59

N/A=not applicable. ^*Two-tailed Fisher's Exact test.