Table 1. Clinicopathological factors and MCAK mRNA expression in 120 colorectal cancers.
| Factors | High expression (%) (n=39) | Low expression (%) (n=81) | P- value |
|---|---|---|---|
| Age (mean±s.d.) | 65.3±12.3 | 66.9±11.3 | 0.49 |
| Gender | |||
| Male | 22 (56.4) | 48 (59.3) | 0.76 |
| Female | 17 (43.6) | 33 (40.7) | |
| Histological grade | |||
| Well | 15 (38.5) | 29 (35.8) | 0.78 |
| Others (moderately, poorly and mucinous) | 24 (61.5) | 52 (64.2) | |
| Tumour size | |||
| <30 mm (small) | 8 (20.5) | 17 (21.0) | 0.95 |
| ⩾30 mm (large) | 31 (79.5) | 64 (79.0) | |
| Serosal invasion | |||
| Absent | 26 (66.7) | 59 (72.8) | 0.49 |
| Present | 13 (33.3) | 22 (27.2) | |
| Lymph node metastasis | |||
| Absent | 14 (35.9) | 53 (65.4) | 0.0023* |
| Present | 25 (64.1) | 28 (34.6) | |
| Lymphatic invasion | |||
| Absent | 22 (56.4) | 53 (65.4) | 0.34 |
| Present | 17 (43.6) | 28 (34.6) | |
| Venous invasion | |||
| Absent | 26 (66.7) | 69 (85.2) | 0.019* |
| Present | 13 (33.3) | 12 (14.8) | |
| Liver metastasis | |||
| Absent | 33 (84.6) | 73 (90.1) | 0.38 |
| Present | 6 (15.4) | 8 (9.9) | |
| Peritoneal dissemination | |||
| Absent | 35 (89.7) | 80 (98.8) | 0.021* |
| Present | 4 (10.3) | 1 (1.2) | |
| Dukes' classification | |||
| A and B | 13 (33.3) | 51 (63.0) | 0.0023* |
| C and D | 26 (66.7) | 30 (37.0) | |
s.d.=standard deviation.
*P<0.05.