The percent identity plot of the Oct4 gene sequences in different mammalian species. Designations: →, the direction of gene transcription; ▬, exons; ▭, CpG islands; ►, dispersed MIR repeats; ▻, other SINE elements; and , long terminal repeats.
Regions of the regulatory elements of vole Oct4 gene are shown in red. Black rectangles denote the exons of vole Oct4 gene; arrow indicates the direction of gene transcription. Various geometric figures (triangles, rectangles) stand for different genetic elements composing the nucleotide sequence. The linear nucleotide sequence of Oct4 gene for each species is plotted on the abscissa axis. Arrangement of dots on the ordinate reflects the homology level between the Oct4 gene sequence of a species and the vole sequence in the range of 50 to 100% (the higher is the dot position, the higher is the homology).Mr, M. rossiaemeridionalis; Mm, Mus musculus; Rn, Rattus norvegicus; Hs, Homo sapiens; Pt, Pan troglodytes; Bt, Bos taurus; and Cf, Canis familiaris.