Table 2. Characteristics of ovarian cancer cases and control women, by gene.
|
BRCA1 |
BRCA2 |
Total |
||||
|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | Cases | Controls | |
| No. | 114 | 225 | 33 | 79 | 147 | 304 |
| Mean no. live births | 2.5 | 2.5 | 2.6 | 2.5 | 2.5 | 2.5 |
| Mean age of (years) first birth among parous | 23.5 | 24.6 | 24 | 24.5 | 23.6 | 24.6 |
| Ever used oral contraceptives (%) | 53 | 63 | 54 | 58 | 53 | 62 |
| Mean years of oral contraceptive use among users | 3.0 | 4.7 | 3.1 | 4.3 | 3.0 | 4.6 |
| Prophylactic bilateral oophorectomy (%) | — | 15 | — | 6 | — | 12 |
| Carrier of Ashkenazi founder mutationa (%) | 32 | 39 | 27 | 29 | 31 | 36 |
a
Mutations 185 del AG, 5382 ins C or 6174 del T.