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. 2004 Feb 3;90(3):705–711. doi: 10.1038/sj.bjc.6601490

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Copyright © 2004 Cancer Research UK

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Experimental design of ZD6126 therapy for gastric cancer growing in an orthotopic site. TMK-1 human gastric cancer cells (10⁶) were injected into the gastric walls of nude mice. Mice were randomised to one of three groups: control, ZD6126 1 day week⁻¹, or ZD6126 5 days week⁻¹. Treatment with ZD6126 (100 mg kg⁻¹) or control began on day 14 by i.p. injection. On day 38, all mice were euthanised.