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. 2004 Feb 3;90(3):705–711. doi: 10.1038/sj.bjc.6601490

Table 1. Treatment of gastric cancer with ZD6126.

    ZD6126 (100 mg kg−1)
  Control Weekly Daily
Body mass (g)±s.e.m. 30.9±0.8 31.3±1.0 29.2±0.7
Tumour volume (mm3)±s.e.m. 440±154 241±39b 79±25a
Tumour mass (g)±s.e.m. 0.5±0.1 0.4±0.1 0.2±0.1b
Incidence of carcinomatosis 10/12 (83.3%) 6/12 (50%) 1/11 (9.1%)c

TMK-1 was injected into the gastric wall on day 0. Therapy with ZD6126, either once a week (weekly) or 5 × per week (daily), was initiated on day 14. Mice were killed on day 38.

a

P<0.002 by Student's t-test.

b

P<0.05 by Student's t-test.

c

P<0.01 by χ2 analysis.