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. 2004 Feb 17;90(4):911–916. doi: 10.1038/sj.bjc.6601492

Table 2. Ifosfamide N-dechloroethylation activity (sum from 2- and 3-dechloroethylifosfamide) with addition of NADPH-generating system and NADPH-generating system+P450-reductase.

NADPH generating system
NADPH generating system+P450-reductase
Tumour sample N-dechloroethylation (pmol min−1 mgprotein−1) Tumour sample N-dechloroethylation (pmol min−1 mgprotein−1)
T4 0.04    
T5 0.21 T5 0.07
T6 0.12 T6 1.46
Eli8 0.11    
    P2 0.25
    P11 0.07