Table 2. Dose-limiting toxicity.
| Toxicity within 28 days | Toxicity at any time | |
|---|---|---|
| 5 mg bd | 1/5 (20%) | 1/5 (20.0%) |
| 10 mg bd | 0/5 | 3/5 (60.0%) |
| 20 mg bd | 0/3 | 1/3 (33.3%) |
| 30 mg bd | 4/9 (44%) | 6/9 (66.7%) |
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