Table 2. Grade 3+4 toxicity (number and % of patients and courses with toxicity).

	Carboplatin				Paclitaxel				Topotecan
	Total patients, N=43	%	Total courses, N=85	%	Total patients, N=41	%	Total courses, N=80	%	Total patients, N=38	%	Total courses, N=145	%
Nonhaematological
Nausea/vomiting	3	7	2	2	0	0	0	0	1	3	1	1
Mucositis	0	0	0	0	1	2	1	1	0	0	0	0
Diarrhoea	1	2	1	1	0	0	0	0	2	5	2	1
Alopecia	0	0	0	0	15	37	22	28	18	47	72	50
Thromboembolic event	2	5	2	2	1	2	2	3	0	0	0	0
Haematological
Anaemia	1	2	1	1	2	5	2	3	6	16	6	4
Neutropenia	2	5	0	0	2	5	3	4	31	82	88	61
Neutropenic sepsis	2	5	2	2	2	5	2	3	5	13	8	6
Thrombocytopenia	1	2	1	1	0	0	1	1	4	11	5	3