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. 2004 Mar 2;90(5):985–990. doi: 10.1038/sj.bjc.6601617

Table 1. Characteristics of the evaluated patients.

Pt. no. Sex Age (years) Prior tumour therapy (best response) Karnofski (%) Clinical status at start Metastasis Number of infusions Response after first cycle Survival (months; until January 2002)
 1 M 68 IFN+Vinbl (PD) 90–100 PD Adrenal 12 PD 6
 2 F 45 IFN+Vinbl (PD) 70 PD Lung and liver 4 PD 2
 3 F 75 None 80 PD Lung 12 PD 4
 4 M 51 None 80 PD Lung, liver and LN 11 PD 3
 5 F 77 None 90 PD Lung 5 PD 2
 6a M 66 IFN+Vinbl (SD) 80 PD Lung and liver 20 SD 18+
      IFN+Vinbl (PD)            
      5FU+CF (PD)            
 7 F 58 Radiation (PD) 90–100 PD Lung 12 PD 18+
 8 M 77 IFN+Vinbl 80 PD Lung and bone 4 PD Date unknown
      5FU+CF            
 9a M 68 IFN+Vinbl (SD) 90–100 PD Lung, pleura, adrenal 20 SD 18+
      5FU+CF (SD)            
10 M 69 IL-2/IFN/5FU (SD) 90–100 PD Lung and liver 12 PD 18+
      IL-2/IFN/5FU red (PD)            
11 M 66 None 90–100 PD Lung and LN 12 PD 17
12 F 67 None 90–100 UN Liver, spleen and LN 12 PD 18+
13 F 64 IFN+Vinbl (PD) 90–100 PD Lung and liver 11 PD 4
14 M 72 None 90–100 PD Lung 7 PD 1
15 M 51 IFN+Vinbl (PD) 90–100 PD Lung, LN, pancreas 12 PD 17+
16 M 54 IFN+Vinbl (PD) 90–100 PD LN, contralateral kidney and psoas muscle 12 SD 17+
      IFN+cis-RA (PD)            
      5FU+CF (PD)            
17 M 67 IFN+Vinbl 80 PD Lung 5 PD 7
18 M 50 IFN (PD) 90–100 PD Lung 12 PD 9
19 M 43 None 90–100 PD Lung and LN 12 PD 8
20 F 60 None 80 UN LN 12 PD 11
21a M 69 None 90–100 UN Lung and LN 20 SD 16+
22a M 70 None 90–100 UN LN 20 SD 13
23a M 61 None 80 PD Lung, LN and Liver 20 SD 16+
24a M 56 IL-2 (SD) 90–100 PD LN 20 SD 15+
      DC vaccination (SD)            
25a F 52 IFN+cis-RA (CR) 90–100 PD Other kidney 20 SD 15+
26 M 69 IL-2/IFN/5FU (PD) 80 PD Lung and LN 12 PD 15+
27a M 57 IL-2/IFN/5FU (PR) 90–100 UN Lung 20 SD 15+
28a F 76 None 90–100 PD Lung and adrenal 20 SD 14
29 M 66 IL-2/IFN/5FU (SD) 80 PD Lung and LN 12 PD 15+
      IL-2 inhalation (PD)            
30 F 65 IL-2/IFN/5FU (PD) 90–100 PD Lung and LN 12 PD 14+
      Toremifene+Vinbl (PD)            
31 F 70 IFN+Vinbl (PR) 90–100 PD Lung 12 PD 14+
      IFN+Vinbl (PD)            
      IFN+Vinbl (PD)            
32 M 76 None 90–100 PD Lung 12 PD 14+
33 M 71 None 80 PD LN and pleura 12 PD 14+
34 M 57 Vaccination (PD) 90–100 PD Lung 12 PD 7
35 M 67 IFN+cis-RA (SD) 90–100 PD Lung and LN 10 PD 5
36a F 73 None 80 PD Lung 20 SD 13+
a

Patients who received extended treatment.

Sex: M=male, F=female; response: PD=progressive disease, SD=stable disease, PR=partial response, CR=complete response, UN=unknown; metastasis: LN=lymphnode; prior treatment: IFN=interferon-alpha, Vinbl=vinblastine, 5FU=5-fluorouracil, CF=calcium folinate, IL-2=interleukin-2, cis-RA=cis-retinoic acid, DC=dendritic cell.