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. 2004 Mar 2;90(5):1025–1029. doi: 10.1038/sj.bjc.6601650

Table 1. Observed (Obs) and expected (Exp) number of cervical intraepithelial neoplasia (CIN3) and cervical cancer (CC) cases and standardised incidence ratios (SIR=Obs/Exp), with 95% confidence intervals (95% CI), among women with at least five children.

  CIN3
CC
Variable Obs Exp SIR 95% CI Obs Exp SIR 95% CI
Parity
5 92 70 1.32 1.06–1.62 111 98 1.13 0.93–1.36
6 52 34 1.55 1.16–2.03 65 56 1.17 0.90–1.49
7 18 12 1.48 0.88–2.34 24 18 1.32 0.84–1.96
8+ 16 15 1.08 0.62–1.76 20 23 0.87 0.53–1.34
 
Age at first birth (years)
<20 51 29 1.74 1.30–2.29 42 23 1.82 1.31–2.46
20–24 93 71 1.31 1.06–1.61 107 94 1.14 0.94–1.38
25–29 27 25 1.09 0.72–1.58 54 59 0.92 0.69–1.20
30+ 7 5 1.33 0.53–2.73 17 20 0.87 0.51–1.39
 
Birth interval (years)
<2.0 68 42 1.62 1.26–2.05 68 55 1.24 0.97–1.58
2.0–3.0 72 50 1.45 1.13–1.82 78 79 0.99 0.78–1.24
3.0+ 38 38 0.99 0.70–1.36 74 62 1.20 0.94–1.50
 
Age at follow up (years)
<40 38 25 1.51 1.07–2.08 17 7 2.36 1.37–3.77
40–49 62 44 1.42 1.09–1.82 40 29 1.36 0.97–1.86
50–64 59 48 1.23 0.94–1.5 106 100 1.07 0.87–1.29
65+ 19 14 1.41 0.85–2.20 57 59 0.96 0.73–1.25