Table 3. SIR for histological types of testicular cancer in the offspring of paternal and fraternal probands.

		Seminoma				Teratoma				All types
Histological types in proband	Age at diagnosis	O	SIR	95% CI		O	SIR	95% CI	O	SIR	95% CI
Paternal proband
Seminoma	0–24	0				3	4.62	0.87	13.69	3	3.78	0.71	11.18
	>24	4	3.52	0.92	9.11	3	3.6	0.68	10.66	7	3.50	1.39	7.26
	All	4	3.18	0.83	8.23	6	4.05	1.46	8.87	10	3.58	1.71	6.61
Teratoma	0–24	0				3	8.64	1.63	25.58	3	7.2	1.36	21.32
	>24	2	4.01	0.38	14.76	0				2	2.28	0.22	8.39
	All	2	3.61	0.34	13.27	3	4.2	0.79	12.45	5	3.87	1.22	9.1
All types	0–24	0				7	6.85	2.71	14.18	7	5.63	2.23	11.66
	>24	6	3.53	1.27	7.73	3	2.42	0.46	7.15	9	3.02	1.37	5.75
	All	6	3.19	1.15	6.98	10	4.42	2.1	8.15	16	3.78	2.16	6.16
Fraternal proband
Seminoma	0–24	1	11.7	0	67.04	3	7.79	1.47	23.07	5	10.29	3.25	24.22
	>24	15	9.65	5.38	15.95	6	6.11	2.2	13.38	21	8.15	5.03	12.47
	All	16	9.75	5.56	15.88	9	6.58	2.98	12.55	26	8.49	5.54	12.45
Teratoma	0–24	0				7	14.35	5.69	29.74	7	11.53	4.57	23.89
	>24	9	6.88	3.12	13.12	9	9.95	4.51	18.98	18	8.02	4.74	12.7
	All	9	6.39	2.9	12.18	16	11.50	6.55	18.71	25	8.76	5.67	12.96
All types	0–24	1	5.27	0	30.2	10	11.16	5.31	20.6	12	10.71	5.51	18.76
	>24	25	8.52	5.51	12.59	15	7.77	4.33	12.84	40	8.1	5.78	11.03
	All	26	8.32	5.43	12.21	25	8.84	5.72	13.07	52	8.58	6.41	11.26

Bold type: 95%CI does not include 1.00. O=observed, SIR=standardised incidence ratio; CI=confidence interval.