Table 1.
Metabolic parameters in control rats, streptozotocin-treated rats (STZ), and streptozotocin-treated diabetic rats supplemented with insulin (STZ+INS)
Parameter | Treatment
|
||
---|---|---|---|
Control | STZ | STZ+INS | |
Body weight, g | 268 ± 7.6 | 210 ± 3.4* | 224 ± 12.1† |
Liver weight, g | 9.3 ± 0.09 | 5.8 ± 0.37* | 8.1 ± 0.31† |
Liver weight/body weight, % | 3.5 ± 0.14 | 2.8 ± 0.17* | 3.6 ± 0.24† |
Plasma glucose, mg/dl | 168 ± 13 | 425 ± 51* | 218 ± 34† |
Liver cholesterol content, mg/g | 2.2 ± 0.08 | 2.7 ± 0.13* | 1.8 ± 0.07† |
Liver triglyceride content, mg/g | 2.7 ± 0.55 | 4.3 ± 0.30‡ | 2.1 ± 0.52† |
Each value represents the mean ± SEM of four male rats.
*P < 0.01 between control and STZ groups.
†P < 0.01 between STZ and STZ+INS groups.
‡P < 0.05 between control and STZ groups.