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. 1999 Nov 23;96(24):13679–13684. doi: 10.1073/pnas.96.24.13679

Figure 5.

Figure 5

(A) Alignment of the human MDR1 and MDR3 sequences of P-glycoprotein with the C219 epitope homologous sequence in c-erbB2. The position of the C219 epitope sequence is indicated. (B) Amino acid positions of the minimal C219 epitope sequence and their tolerance for sequence change (19). (C) Sequence alignment of HisP with the C-terminal ATP-binding domain of P-glycoprotein (MDR3). The position of helix α6 is indicated. Black and gray boxes indicate identical and homologous residues, respectively.