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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: J Mol Graph Model. 2007 Nov 17;26(8):1189–1201. doi: 10.1016/j.jmgm.2007.11.001

Figure 4. Interaction vs. ligand binding affinity at S1P4.

Figure 4

S1P4 complex with FTY720P (A), phosphonate (B) and SEW2871 (C). Ball and stick atoms represent ligands and stick atoms represent residues required for ligand binding. Non-polar hydrogens are omitted for clarity. S1P4 interactions with ligands in order FTY720P (A) > S1P ~ benzimidazole > Phosphonate (B) > Azetidine > SEW2871 (C) agree with binding affinity observed for these ligands (Table 1).