Table III.

V_H6 repertoire analysis of the splenic B cell subsets of an 8-mo-old child

Donor	B cell subset	Transcripts	Number of peaks analyzeda	Total number of sequences	Number of different VDJ junctions	Clonal diversityb	P valuec
						%
D3	IgD+CD27+	VH6 μ	4	68	58	85
	Naives	VH6 μ	3	56	36	64
	IgD−CD27+ (switched + GC)	VH6 γ	3	50	12	24	7 × 10−11
	CD38+CD24− (GC)	VH6 μ	3	55	8	14.5	2 × 10−14
		VH6 γ	4	76	5	6.5	10−20

^aThe peaks that were analyzed are identified by an asterisk in Fig. 2.

^bNumber of different VDJ among all sequences.

^cStatistical significance (see Materials and methods) of differences in clonal diversity between IgD⁺CD27⁺ and IgD⁻CD27⁺ or GC cells from the same donor.