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. 2008 Jun 9;205(6):1331–1342. doi: 10.1084/jem.20071555

Table IV.

Somatic mutations in JH4-JH5 introns flanking VDJH4 rearrangements from splenic and blood B cell subsets

Donors Age
(months)
Tissue CD20-positive
B cell
subsets
Number of sequences
Mutations




Total
Mutated
Range
Number
Frequency/
total
sequences
Frequency/
mutated
sequences
% %
D3 8 spleen IgD+CD27+ 21 10
(48%)
0–6 23 0.32 0.67
IgDCD27+ 20 19
(95%)
0–14 105 1.54 1.55
blood IgD+CD27+ 20 12
(60%)
0–7 37 0.54 0.90
IgDCD27+ 18 13
(72%)
0–16 103 1.67 2.32
D1 11 blood IgD+CD27+ 20 15
(75%)
0–17 79 1.16 1.54
IgDCD27+ 20 18
(90%)
0–22 117 1.71 1.90
D2 11 blood IgD+CD27+ 18 15
(83%)
0–16 116 1.89 2.27
IgDCD27+ 17 16
(94%)
0–21 127 2.19 2.32
D4 22 spleen IgD+CD27+ 25 12
(48%)
0–14 40 0.51 1.09
IgDCD27+ 14 13
(93%)
0–23 91 1.90 2.05