Table 1.
Cytokine targets in human inflammatory and autoimmune diseases
| Cytokine | Disease | Therapeutic effect | References |
|---|---|---|---|
| IL-1 | NOMID | Yes | [151] |
| FCA | Yes | [152] | |
| Muckle-Wells | Yes | [153] | |
| SoJIA | Yes | [77] | |
| Gout | Yes | [78] | |
| Type II diabetes | [79] | ||
| IL-6 | SoJIA | Yes | [89] |
| RA | Yes | [90] | |
| IL-12/23 | Crohn's | Yes | [98] |
| MS | Yes | [154] | |
| Psoriasis | Yes | [107,155] | |
| IL-17 | RA | Not tested | |
| MS | Not tested | ||
| TNF-α | RA | Yes | [113] |
| JIA | Yes | [156] | |
| Crohn's | Yes | [157] | |
| Psoriasis | Yes | [114] | |
| IFN-α | SLE | Not tested | |
| Myositis | Not tested | ||
| Psoriasis | Not tested | ||
| Sjogren's | Not tested |