Table 1.
Overrepresented GO Biological Processes in the brain
| GO Biological Process | Count | % | p-value |
| protein folding | 19 | 2.64% | 0.004 |
| ubiquitin-dependent protein catabolism | 12 | 1.67% | 0.016 |
| modification-dependent protein catabolism | 12 | 1.67% | 0.022 |
| M phase | 28 | 3.89% | 0.025 |
| cellular metabolism | 315 | 43.81% | 0.025 |
| proteolysis during cellular protein catabolism | 12 | 1.67% | 0.032 |
| cellular protein catabolism | 12 | 1.67% | 0.032 |
| response to stress | 29 | 4.03% | 0.034 |
| catabolism | 33 | 4.59% | 0.034 |
| nuclear migration | 5 | 0.70% | 0.036 |
Top 10 significant GO biological processes that were overrepresented in expression profiling of the brains. One major pathway, involved in purine metabolism, was significantly overrepresented by our data set, as well as genes associated with metabolism and stress response.