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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Dev Biol. 2008 Feb 29;317(1):282–295. doi: 10.1016/j.ydbio.2008.02.037

Figure 7. BMP2 induces Twist1, Cad11, Postn, and Mmp2 expression in endocardial cushion cells.

Figure 7

Endocardial cushion cells were cultured with or without the addition of soluble recombinant BMP2 or Noggin, a BMP inhibitor. Addition of BMP2 resulted in increased Twist1, Cad11, Postn, and Mmp2 expression relative to untreated controls, while addition of Noggin attenuated that response as measured by real time RT-PCR. Asterisks represent a statistically significant difference compared to untreated control groups (n=4, P<0.01). Error bars represent standard error of the mean.