Figure 9. Hip1r-deficient mice are hypergastrinemic.

(A) Gastrin transcript abundance was determined by qRT-PCR analysis of gastric antral RNA samples from 6-month-old WT and Hip1r-deficient mice. Data (mean ± SEM) were normalized to Gapdh expression in the same samples and reported as fold change relative to WT. n = 3. (B) Plasma gastrin levels were measured in 2- to 6-month-old mice by RIA in WT and Hip1r-deficient mice (n = 8–10). *P < 0.05, **P = 0.0001 versus WT.