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. 2008 May 29;27(12):1671–1681. doi: 10.1038/emboj.2008.105

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Copyright © 2008, European Molecular Biology Organization

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation or the creation of derivative works without specific permission.

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Tumour development in H. felis-infected K19-Wnt1 mouse stomach. K19-Wnt1 (A–D) and wild-type (E–H) mouse stomach infected with H. felis for 20 weeks. (A, E) Macroscopic photographs. The arrows in (A) indicate gastric tumours that developed in the infected K19-Wnt1 mice. H&E staining at low magnification (B, F) and high magnification (D, H). Immunostaining results for macrophage marker F4/80 (C, G). The arrows in (B, F) indicate submucosal infiltration. The arrowheads in (D) indicate dysplastic epithelial cells. Bars in (B, F) and (C, D, G, H) indicate 200 and 40 μm, respectively.