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. 2008 May 29;27(13):1875–1885. doi: 10.1038/emboj.2008.111

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Copyright © 2008, European Molecular Biology Organization

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation or the creation of derivative works without specific permission.

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DSB resection is regulated by both NHEJ-dependent and NHEJ-independent mechanisms in G1. Cells of strains YCZ101 (1cs, ARS607::HOcs matHOcsΔ), YCZ136 (1cs, ARS607::HOcs matHOcsΔ dnl4Δ) and YCZ202 (2cs, ARS607::HOcs MATHOcs dnl4Δ) were used. 1cs, one HO cut site. (A) Analysis of DSB processing. (B, C) Immunoblot, Rad53 autokinase and DSB assays.