Table 5.

Patient characteristics to assess at baseline and at 6-monthly follow-up assessments

Target symptoms
Positive symptoms	Hallucinations, delusions, behavioral abnormalities, disorganization
Negative symptoms	Social isolation, reduced motivation, reduced speech, reduced pleasure
Mood	Low mood, suicidal thoughts
Cognition	Memory problems, attention deficits, concentration difficulties
Target aspects of daily life
Personal care	Poor hygiene (washing, bathing, grooming), appearance, clothing
Social	Most of day alone, little interaction with friends/family
Housing	Frequent moves, living on the street
Nutrition	Poor diet, frequently missing meals, excessive consumption of high-fat fast foods
Vocational	Difficulties finding and/or keeping up with job/school
Organizational/social	Difficulty connecting with community supports
Overall	Recurring need for hospitalization
Quality of life	As perceived by informants, as perceived by patient
Target side effects
Movements	Akathisia, parkinsonism, tardive dyskinesia, tremor
Cardiovascular	Hypotension
Endocrinea	Gynecomastia, galactorrhea, oligomenhorrhea, amenhorrhea
Metabolica	Weight gain, lipid elevation, glucose intolerance/diabetes
Sexual functioning	Loss of libido, impotence
Emotional/Cognitive	Flattened affect, difficulties with concentration and memory
Sleep	Sedation, insomnia

^aMonitor if these were problems prior to treatment with ziprasidone.