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. Author manuscript; available in PMC: 2008 Jun 5.
Published in final edited form as: Diabetes. 2006 Dec;55(12):3366–3371. doi: 10.2337/db06-0550

FIG. 3.

FIG. 3

Obesity phenotype of an 8-year-old girl with haploinsufficiency at the BDNF locus. A: Weight gain compared with normal U.K. percentiles for girls. B: Food intake at an 18-MJ ad libitum test meal, expressed per kilogram lean body mass, compared with subjects with mutations in other genes responsible for obesity syndromes and controls. Food intake is expressed per kilogram lean body mass measured by dual-energy X-ray absorptiometry to allow comparison between subjects of different ages. C: Measured basal metabolic rate measured by indirect calorimetry compared with predicted values. The BDNF-haploinsufficient patient is highlighted and compared with age- and BMI-matched obese control subjects.