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. 2008 May 27;336(7656):1295–1297. doi: 10.1136/bmj.39549.548831.AE

Table 2.

 Primary endpoints at 6, 15, and 24 months post-randomisation (HADS depression scale)

Time point Intervention (n=116) Control (n=120) Unadjusted analysis* Adjusted analysis†
No Mean (SD) No Mean (SD) Mean difference (95%CI) P value Least squares mean difference (95%CI) P value
6 months 104 6.03 (3.63) 113 5.84 (3.96) −0.193 (−1.21 to 0.83) 0.709 −0.485 (−1.23 to 0.26) 0.201
15 months 96 6.03 (4.00) 106 6.71 (4.18) 0.676 (−0.46 to 1.81) 0.241 0.468 (−0.50 to 1.44) 0.342
24 months 93 6.25 (4.12) 97 6.35 (4.59) 0.103 (−1.15 to 1.35) 0.871 −0.207 (−1.32 to 0.90) 0.713

HADS=hospital anxiety and depression scale.

*Based on two sample t test.

†Based on general linear model adjusting for baseline difference, kinship, and area (that is, stratification variables).