Figure 2. Tumorigenic UM-C4 cells are enriched in residual tumors following CPA administration.

A) Limiting dilution analysis of unfractionated UM-C4 tumor cells was used to calculate TG cell frequency using Poisson distribution statistics (±95% confidence level; *P = 0.0016). B) Percentage of human ESA⁺CD44⁺ and ESA⁺CD44⁺CD166⁺ cells in secondary tumors arising from residual tumorigenic cells transplanted serially in limiting dilution following vehicle or CPA treatment regimens.