TABLE 1.
Effect of salmonella injection on nine different transplantable tumors in C57BL/6 mice
Tumor | Treatment | Day 21* average tumor size (mm2) | % Decrease | Day 27* average tumor size (mm2) | % Decrease |
---|---|---|---|---|---|
B16 | Salmonella | 172 ± 21 | 61.3 | 226 ± 10 | ND† |
PBS | 444 ± 42 | ND† | |||
MC-38 | Salmonella | 50 ± 6 | 6.8 | 83 ± 12 | 47.8 |
PBS | 53 ± 9 | 159 ± 21 | |||
MCA-101 | Salmonella | 140 ± 13 | 25.5 | 228 ± 34 | 22.1 |
PBS | 188 ± 6 | 293 ± 14 | |||
MCA-102 | Salmonella | 143 ± 16 | 8.5 | 206 ± 96 | 32.1 |
PBS | 156 ± 25 | 304 ± 35 | |||
MCA-105 | Salmonella | 51 ± 8 | 47.5 | 89 ± 15 | 47.7 |
PBS | 97 ± 5 | 170 ± 10 | |||
MCA-106 | Salmonella | 46 ± 8 | 45.2 | 80 ± 12 | 42.7 |
PBS | 85 ± 16 | 139 ± 22 | |||
MCA-203 | Salmonella | 94 ± 4 | 23.3 | 135 ± 2 | 37.3 |
PBS | 123 ± 6 | 216 ± 20 | |||
MCA-205 | Salmonella | 97 ± 16 | 47.8 | 152 ± 26 | 49.4 |
PBS | 185 ± 24 | 301 ± 48 | |||
MCA-207 | Salmonella | 73 ± 13 | −10.6 | 103 ± 17 | 11.1 |
PBS | 66 ± 18 | 116 ± 16 |
Mean ± standard error.
All control B16 melanoma mice died of progressive tumor by day 27.
PBS, phosphate buffered saline.