TABLE 4.
Hematologic toxicities associated with the treatment
Nadir* (cells/mm3)
|
Time to recovery† (days)
|
|||||
---|---|---|---|---|---|---|
Patient | ANC | ALC | Plat (×10−3) | ANC >500 | ALC >200 | Plat >20 |
1 | 3 | 1 | 18 | 6 | 7 | 5 |
2 | 303 | 17 | 83 | 5 | 14 | —‡ |
3 | 20 | 30 | 220 | 6 | 6 | — |
4 | 3 | 3 | 14 | 6 | 15 | 5 |
5 | 1 | 5 | 11 | 8 | 11 | 6 |
6 | 7 | 13 | 18 | 6 | 9 | 6 |
7 | 3 | 4 | 45 | 6 | 8 | — |
8 | 8 | 9 | 74 | 5 | 7 | — |
9 | 13 | 11 | 8 | 7 | 7 | 7 |
10 | 2 | 5 | 14 | 6 | 7 | 10 |
11 | 5 | 0 | 12 | 9 | 8 | 10 |
12 | 6 | 5 | 19 | 8 | 9 | 8 |
13 | 1 | 1 | 7 | 11 | 12 | 12 |
14 | 9 | 2 | 18 | 6 | 6 | 8 |
15 | 7 | 3 | 9 | 7 | 8–50 | 6 |
Normal ranges for these parameters are ANC (1.32–7.5 × 103 per mm3), ALC (0.46–4.7 × 103 per mm3), and platelets (154–345 × 103 per mm3).
Values were obtained at least every other day unless a range is given.
Platelet count was never below 20 × 103 per mm3.
ALC, absolute lymphocyte counts; ANC, absolute neutrophil counts.