Figure 2.

8-pCPT enhances LTP maintenance, without affecting LTP induction or basal synaptic transmission. (A) Application of 8-pCPT alone has no effect on basal synaptic transmission. (B) Pairing 8-pCPT with 1 × 100 Hz stimulation enhances maintenance, but not induction, of LTP relative to controls. (C) Summary histogram for these experiments comparing levels of potentiation 120 min after HFS (**P < 0.01). All sample fEPSP traces were sampled at time points A and B on graphs. Calibration bars: 5 mV, 2 msec.