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. 2008 Jun 6;283(23):15647–15655. doi: 10.1074/jbc.M800543200

TABLE 2.

Average rolling velocities (μm/s) of wild-type, CD44-knockdown, CEA-knockdown, and CEA/CD44-double knockdown LS174T cells (106/ml) perfused over a surface coated with 0.75 μg/ml E-selectin at the physiological shear stress levels of 1.0 or 2.0 dynes/cm2

Data represent the mean ± S.E.

Average rolling velocity
1.0 dyne/cm2 2.0 dynes/cm2
μm/s
Wild-type LS174T 5.3 ± 0.3 7.2 ± 0.4
CD44-knockdown LS174T 5.1 ± 0.3 6.9 ± 0.5
CEA-knockdown LS174T 5.2 ± 0.4 7.1 ± 0.5
CEA/CD44-knockdown LS174T 5.2 ± 0.4 10 ± 1a,b,c
a

Values are p < 0.05 with respect to wild-type LS174T cells.

b

Values are p < 0.05 with respect to CD44-knockdown LS174T cells.

c

Values are p < 0.05 with respect to CEA-knockdown LS174T cells.