TABLE 1.

Effects of R1 treatment on disease progression ErS: early stage; EdS: end stage; n = 14 for the R1-infused group; n = 16 for the PBS-infused group. The numbers are average days ± standard deviation. Onset-to-ErS and onset-to-EdS periods were calculated from individual animals in each group and averaged. Statistical comparisons between R1 and PBS groups were done using the Wilcoxon rank sum test, and the p values are the following: onset, 0.200; ErS, 0.085; EdS, 0.022; Onset to ErS, 0.024; Onset to EdS, 0.004.

Treatment	Onset	ErS	EdS	Onset to ErS	Onset to EdS
R1	100 ± 13	122 ± 7	133 ± 9	23 ± 11	33 ± 12
PBS	105 ± 6	119 ± 7	125 ± 10	14 ± 6	20 ± 8