Table 2.
Summary of transgenic animals producing BChE/hSA fusion protein
| Transgenic animal | Animal ID | Generation | Sex | Transgene copy number | Integration site | Expression in milk (g/liter)* |
| Mouse | 307-1 | F0 | F | ~40 | ND | 0.27 |
| 307-1A2 | F1 | F | 1–2 | ND | 0.40 | |
| 307-1A7 | F1 | F | 8–10 | ND | 0.41 | |
| 307-1A7A2 | F2 | F | 8–10 | ND | 0.24 | |
| 307-1A7A4 | F2 | F | 1–2 | ND | 0.41 | |
| Goat | 2176 | F0 | F | 18–28 | 2 | 0.06 |
| 2177 | F0 | F | 6–10 | 1–2 | 1.10 | |
| 2178 | F0 | F | 18–28 | 2–3 | 0.07 | |
| 2229 | F0 | F | 10–14 | 1–2 | 0.07 | |
| 2231 | F0 | F | 10–14 | 1–2 | 0.04 | |
| 2232 | F0 | F | 10–14 | 1–2 | 0.09 | |
| 2233 | F0 | F | 10–14 | 1–2 | 0.08 | |
| 2234 | F0 | F | 10–14 | 1–2 | 0.35 | |
| 2236 | F0 | F | 10–14 | 1–2 | 0.10 | |
| 2237 | F0 | F | 10–14 | 1–2 | 0.23 | |
| 2238 | F0 | F | 10–14 | 1–2 | 0.09 | |
| 2239 | F0 | F | 10–14 | 1–2 | 0.11 | |
*The concentrations for expression of BChE/hSA, estimated by densitometry where 720 units = 1 mg of purified plasma huBChE. [29], were the average of two independent assays. ND = not determined.