TABLE 2.

Rat survival with compound cotreatment^a

Compound	Dose (mg)/rat	Survival (no. of mice that survived/total no.)	Time to death (min)	P valueb
PBS	NAc	0/20	72-100
5b	1.25	6/6		<0.0001
5b	0.25	0/5	130-239
5g	0.25	6/6		<0.0001
5g	0.085	6/6		<0.0001
5g	0.017	2/3	623	0.01186
14b	1.25	4/4		<0.0001
14b	0.25	7/7		<0.0001
14b	0.085	6/6		<0.0001
14b	0.017	2/3	285	0.01186
14c	0.25	6/6		<0.0001
14c	0.085	6/6		<0.0001
14c	0.017	2/3	382	0.01186

^aFischer rats were injected i.v. with LT (10 μg PA plus 10 μg LF) mixed with the listed compounds or PBS, and survival was monitored over 8 h.

^bP values were calculated on the basis of the results for each group relative to those for the PBS-treated controls by the use of Fisher's test (two tailed).

^cNA, not applicable.