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Time-kill studies conducted with C. parapsilosis ATCC 22019 and four isolates of C. glabrata (4198, 4205, 4293, and 4370). Symbols: crosses, controls; open symbols, one-half the MIC of the drug; solid symbols, eight times the MIC of the drug; squares, AMB; triangles, CAS; circles, POS; diamonds, FLC. The solid lines represent a >99.9% growth reduction compared with the initial inoculum size (fungicidal effect). The limit of detection is 20 CFU/ml (dotted lines).
