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. Author manuscript; available in PMC: 2009 May 8.
Published in final edited form as: Cell Stem Cell. 2008 May 8;2(5):484–496. doi: 10.1016/j.stem.2008.03.004

Figure 3. Pbx1-deficient stem cells display increased cycling and reduced quiescence.

Figure 3

(A) Control or mutant mice were injected ip with BrdU and sacrificed 2 hrs later. Representative FACS analyses on the left show BrdU and 7-AAD incorporation in KSL cells. Graphs on the right represent the % of BrdU+ cells in LT-HSCs, ST-HSCs and MPP cells in three independent experiments (*p=0.06, **p<0.04). (B) Left: representative FACS analysis of PY/Hoechst staining on KSL cells (top) or LT-HSC (bottom). Right: % of KSL cells (top) or LT−. HSCs (bottom) in G0, G1, and S phase (n=2, with bars representing the range).